VEGFR-1belongstoafamilyoffivereceptortyrosinekinasereceptorsthatarespecifictoanumberofangiogenicfactorsincludingVEGFandPDGF,andarethereforethoughttoplayaroleintheangiogenicprocess.VEGFR-1isexpressedintwoforms,predominantlyonendothelialcells,givingrisetoafull-lengthmembraneboundreceptorandatruncatedsolublereceptor.ElevatedlevelsofthesolubleformofthisVEGFreceptormaybeusedinthediagnosisofpathologicalconditions.||Source:|Recombinantcorrespondingtoaa31-328fromhumanVEGFR,fusedto6xHis-tagatN-terminal,expressedinE.coli.||Applications:|SuitableforuseinWesternBlotasacontrol.Otherapplicationsnottested.||RecommendedDilution:|Optimaldilutionstobedeterminedbytheresearcher.||StorageandStABIlity:|Maybestoredat4°Cforshort-termonly.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.Source:E.coli|Purity:Purified(SDS-PAGE).|Concentration:Asreported|Form:Suppliedasaliquidin25mMTris-HCl,pH6.8,50mMDTT,1%SDS,0.1%BromophenolBlue,2.5%glycerol.||ImportantNote:Thisproductassuppliedisintendedforresearchuseonly,notforuseinhuman,therapeuticordiagnosticapplicationswithouttheexpressedwrittenauthorizationofUnitedStatesBIOLOGical.

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