Thisgeneisamemberofthecalpainsmallsubunitfamily.Calpainsarecalcium-dependentcysteineproteinasesthatarewidelydistributedinmammaliancells.Calpainsoperateasheterodimers,comprisingaspecificlargecatalyticsubunit(calpain1subunitinCalpainI,andcalpain2subunitinCalpainII),andacommonsmallregulatorysubunitencodedbythisgene.ThisencodedproteinisessentialforthestABIlityandfunctionofbothcalpainheterodimers,whoseproteolyticactivitiesinfluencevariouscellularfunctionsincludingapoptosis,proliferation,migration,adhesion,andautophagy.Calpainshavebeenimplicatedinneurodegenerativeprocesses,suchasmyotonicdystrophy.Apseudogeneofthisgenehasbeendefinedonchromosome1.Alternativesplicingresultsinmultipletranscriptvariants.||Applications:|SuitableforuseinELISA,WesternBlot,Immunohistochemistry.Otherapplicationsnottested.||RecommendedDilution:|WesternBlot:1:500–1:2000|Immunohistochemistry:1:50–1:200|Optimaldilutionstobedeterminedbytheresearcher.||StorageandStability:|Maybestoredat4°Cforshort-termonly.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Aliquotsarestablefor12monthsafterreceipt.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.

usbio的生化试剂，抗体，重组蛋白，细胞培养基和分子生物学试剂盒几乎用于所有科学应用和环境，包括基因组研究，生物技术，药物开发和疾病诊断。 恭喜苏州蚂蚁淘获得usbio2020年授权书，成为usbio中国代理，购买usbio,请认准usbio代理-苏州蚂蚁淘！