Usbio//25mg/217293
商品编号：
217293
品牌：
USbiological
市场价：
¥9780.00
美元价：
4156.50
产品分类：
其他试剂
公司分类：
Other_reagents
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
A cell-permeable pyridinylphenyl-methanone compound that is reported to effectively upregulate SMN (survival of motor neuron) protein level in 3 out of 4 SMA (spinal muscular atrophy) patient-derived fibroblast lines (by 71% to 93% increase in 48h; 5ug/ml), but not HT1080, 293T, A549, two human ESC-MN lines, MEF, mESC-MN, rat PC12, or rat ST14A cells. Shown to preferentially stimulate cellular Erk (Thr202/Tyr204) over Akt (Ser473) phosphorylation in SMA fibroblast line 9677 in a time-dependent manner (tmax = 24h; 10ug/ml), indicative of Ras-Raf-MEK signaling pathway activation.||Solubility:|DMSO||Primary Target:|Ras||Storage and Stability:|May be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
品牌介绍
usbio的生化试剂，抗体，重组蛋白，细胞培养基和分子生物学试剂盒几乎用于所有科学应用和环境，包括基因组研究，生物技术，药物开发和疾病诊断。
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