USP25 (Ubiquitin Specific Protease 25) is a deubiquitinating enzyme of the C19 family that is expressed in many human tissue types. USP25 activity is modulated by a sumoylation event that is dependent on the presence of a SUMO-interaction domain (SIM) located in the amino-terminal region of all USP25 isoforms. Sumoylation occurs within one of two ubiquitin interaction motifs (UIMs) that are required for efficient in vitro hydrolysis of polyubiquitin chains (K48-linked or K63-linked) by USP25. While sumoylation impairs USP25 activity again polyubiquitin substrates, it does not affect its hydrolysis of ubiquitin-AMC. This protein contains a C-terminal 6-His tag.||Source:|Recombinant protein corresponding to human USP25, fused to 6-his tag at C-terminal.||Molecular Weight: |~123kD||Storage and Stability:|Aliquot to avoid repeated freezing and thawing and store at -70°C. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

usbio的生化试剂，抗体，重组蛋白，细胞培养基和分子生物学试剂盒几乎用于所有科学应用和环境，包括基因组研究，生物技术，药物开发和疾病诊断。 恭喜苏州蚂蚁淘获得usbio2020年授权书，成为usbio中国代理，购买usbio,请认准usbio代理-苏州蚂蚁淘！