LYN is a 56kD tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues. LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction. Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase.||Source:|Recombinant protein corresponding to human LYN B, fused to GST-Tag at N-terminal expressed in Insect cells.||Molecular Weight:|~85kD||Specific Activity:|235nmol/min/mg as per activity assay protocol.||Endotoxin:|<1EU/ug (LAL)||Storage and Stability:|Aliquot to avoid repeated freezing and thawing and store at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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