MIG (CXCL9) protein belongs to the family of chemotactic cytokines known as chemokines. The synthesis of MIG is specifically induced in macrophages and in other cells by IFN-gamma. Human neutrophils produce mig in response to IFN-gamma in combination with either TNF-alpha or bacterial lipopolysaccharides and this response is blocked by IL-10 and IL-4. MIG is a chemoattractant for stimulated but not resting T cells, however it is not active on neutrophils or monocytes.||Source:|Recombinant protein corresponding to human MIG expressed in E. coli.||Molecular Weight: |~11kD||Biological Activity:|Determined by its ability to chemoattract human peripheral blood T lymphocytes using a concentration range of 10-80ng/mL.||Endotoxin:|<1EU/ug (LAL)||Storage and Stability:|Lyophilized powder may be stored at -20°C. Stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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