This protein is a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This endosomal protein regulates the cell-surface expression of epidermal growth factor receptor. This protein also has a role in sorting protease-activated receptor-1 from early endosomes to lysosomes. This protein may form oligomeric complexes with family members. ||Species: Homo sapiens||Source: E. coli||Primary Sequence (aa): 434||Domain (aa): Full-length||Tag/Fusion Partner: T7 Tag||Applications: Suitable for use in ELISA as an Antigen, Ligand, or Assay Standard. Other applications not tested.||Quality Control: SDS-PAGEStorage and Stability: May be stored at 4°C for short-term only. For long-term storage, aliquot to avoid repeated freezing and thawing and freeze at -70°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquots are stable for at least 12 months. ||Important note: This recombinant enzyme has NOT been tested with regard to biological activity.

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