TheATPbindingcassette(ABC)superfamilyofmembranetransportersisoneofthelargestproteinclassesknown,andcountsfornumerousproteinsinvolvedintraffickingofBIOLOGicalmoleculesacrossmembranes,host-defensemechanismtoxenobiotics.ThefirstknownmemberswereP-glycoprotein(P-gp)andmultidrugresistantprotein(MRP),causemultidrugresistancewhentransfectedintodrug-sensitivecells.Inaddition,increasingnumbersofABCproteinshaverecentlybeenidentified.ThehumanABCG1(ABC,subfamilyG,member1)geneencodesamemberofABCsuperfamilythatmediatestheATP-dependenttranslocationofvarietyofamphiphilicandlipophilicmolecules.ABCGproteinswereabletotransportsubstancesacrosscellularmembranesandagainstconcentrationgrADIenttheyrequireaninputofenergy,whichrequiresthehydrolysisofATP,directlyorindirectly.||ABCG1a678aaproteininhuman(chr21q22.3),666aainmouse,predominantlyexpressedinmanytissues,intheintracellularcompartmentsmainlyassociatedwithendoplasmicreticulumandGolgicomplex.Itshows26%sequencehomologywithABCG2protein.ABCG1proteinisinvolvedinmacrophagelipidhomeostasis,anactivememberofmacrophagelipidexportcomplex.||Source:|14-aapeptidefromMouseABCG1conjugatedtoKLH.~C-terminus,Extracellular||Applications:|SuitableforuseinELISA.Otherapplicationsnottested.||RecommendedDilution:|ELISA:ControlpeptidecanbeusedtocoatELISAplatesat1ug/mlanddetectedwithantibodies(0.5-1ug/mlforaffinitypure).|Optimaldilutiondeterminedbytheresearcher.||StorageandStABIlity:|Maybestoredat4°Cforshort-termonly.Forlong-termstorage,storeat-20°C.Aliquotsarestableforatleast6monthsat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.

usbio的生化试剂，抗体，重组蛋白，细胞培养基和分子生物学试剂盒几乎用于所有科学应用和环境，包括基因组研究，生物技术，药物开发和疾病诊断。 恭喜苏州蚂蚁淘获得usbio2020年授权书，成为usbio中国代理，购买usbio,请认准usbio代理-苏州蚂蚁淘！