Human Adenoviruses (HAdV) are non-enveloped, non-segmented double stranded DNA viruses, belonging to the genus Mastadenovirus within the Adenoviridae family of viruses. Human Adenoviruses have been further classified into seven species groups A- G. Since the discovery of adenovirus in human adenoid tissue in 1953, by Wallace Rowe and colleagues, more than 50 serotypes of HAdV and 70 genotypes have been identified (Cook, J). Hexon protein is the largest and most abundant structural protein in the adenovirus capsid. Human adenoviruses are globally widespread and ubiquitous in the environment. HAdV can persist in the environment and are resistant to most household disinfectants. Transmission of HAdV occurs primarily via the fecal-oral route, with contaminated water and food being the primary source of infection. HAdV may also be spread through contact with contaminated surfaces and through aerosol droplets from an infected individual. Human adenoviruses commonly cause respiratory disease but some HAdV serotypes cause gastrointestinal disease, conjunctivitis and cystitis. The clinical disease caused by HAdV infection varies depending on the HAdV type. In immunocompromised patients, HAdV infection can cause severe clinical symptoms that may lead to respiratory failure, neurological disease and death (CDC).||Applications: |Suitable for use in ELISA. Other applications not tested.||Recommended Dilution:|Optimal dilutions to be determined by the researcher.||Storage and Stability:|May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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