The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma. Recombinant human TFF2 is a polypeptide of 106aa residues, which includes a 40aa trefoil motif containing three conserved intramolecular disulfide bonds.||Source:|Recombinant protein corresponding to human TFF2, expressed in E. coli. ||Molecular Weight: |~12.0kD||Biological Activity:|Determined by its ability to chemoattract human monocytes using a concentration range of 1.0-10.0ug/ml.||Endotoxin:|<0.1ng/ug||Storage and Stability:|Lyophilized powder may be stored at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 6 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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