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Usbio/301773 Rabbit Anti-Tau, Phosphorylated (Ser208/210)/301773/50ul
Usbio/301773 Rabbit Anti-Tau, Phosphorylated (Ser208/210)/301773/50ul
商品编号：
301773
品牌：
USbiological
市场价：
¥11980.00
美元价：
5091.50
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Tauopathiesareagroupofdiversedementiasandmovementdisorderswhichhaveacommonpathologicalfeatureinthattheyalldisplaythepresenceofintracellularaccumulationofabnormalfilamentsoftauprotein.FurThermore,theseaccumulatedtauproteinsalldisplayanabnormalphosphorylationpatternthatmaybediseasespecific.Asanexample,Amyotrophiclateralsclerosis(ALS,alsoreferredtoasCharcot’sdiseaseorLouGehrig’sdisease)isthemostcommonformofprogressivemotorneurondiseaseinNorthAmerica.ALSgraduallydisablesthepatient’svoluntarymotormusclecontroluntilitbecomesfatal.
Applications:|SuitableforuseinELISA,WesternBlot,Immunohistochemistry.Otherapplicationsnottested.
RecommendedDilution
WesternBlot:1:10,000Immunohistochemistry:1:1000Optimaldilutionstobedeterminedbytheresearcher.
StorageandStABIlity
Lyophilizedpowdermaybestoredat-20°C.Stablefor12monthsafterreceiptat-20°C.ReconstitutewithddH2O.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Reconstitutedproductisstablefor12monthsat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.
References
1.Gohar,M.,Yang,W.,Strong,W.,Volkening,K.,Leystra-Lantz,C.,andStrong,M.J.(2009).Tauphosphorylationatthreonine-175leadstofibrilformationandenhancedcelldeath:implicationsforamyotrophiclateralsclerosiswithcognitiveimpairment.JNeuRochem108,634-643.2.Strong,M.J.,Yang,W.,Strong,W.L.,Leystra-Lantz,C.,Jaffe,H.,andPant,H.C.(2006).TauproteinhyperphosphorylationinsporADIcALSwithcognitiveimpairment.Neurology.Neurology66,1770-1771.品牌介绍
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