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Usbio/301778 Mouse Anti-Tau, Phosphorylated (Tyr18)/301778/100ug
Usbio/301778 Mouse Anti-Tau, Phosphorylated (Tyr18)/301778/100ug
商品编号：
301778
品牌：
USbiological
市场价：
¥14500.00
美元价：
6162.50
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
TauopathiesareagroupofdiversedementiasandmovementdisorderswhichhaveacommonpathologicalfeatureinthattheyalldisplaythepresenceofintracellularaccumulationofabnormalfilamentsofTauprotein.WhiletheabnormalphosphorylationofTauonserineandthreoninehasbeenwellestablishedinthediseaseprocess,itsphosphorylationontyrosine18hasonlyrecentlybeendescribedaspresentinbrainswithAlzheimer’sdisease(AD).
Applications:|SuitableforuseinImmunofluorescence,WesternBlot,Immunohistochemistry.Otherapplicationsnottested.
RecommendedDilution
Immunofluorescence:1:2000-1:5000WesternBlot:1:1000-1:5000Immunohistochemistry:1:1000-1:5000Optimaldilutionstobedeterminedbytheresearcher.
StorageandStABIlity
Lyophilizedpowdermaybestoredat-20°C.Stablefor12monthsafterreceiptat-20°C.ReconstitutewithddH2O.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Reconstitutedproductisstablefor12monthsat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.
References
1.Bhaskar,K.,Hobbs,G.A.,Yen,S.A.,andLee,G.(2010).Tyrosinephosphorylationoftauaccompaniesdiseaseprogressionintransgenicmousemodelsoftauopathy.NeuropatholApplNeurobiol36,462-477.|2.Lee,G.,Thangavel,R.,Sharma,V.M.,Litersky,J.M.,Bhaskar,K.,Fang,S.M.,Do,L.H.,AndreADIs,A.,Hoesen,G.V.,andKsiezak-Reding,H.(2004).Phosphorylationoftaubyfyn:implicationsforAlzheimer'sdisease.JNeurosci24,2304-2312.品牌介绍
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