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130268-FITC Mouse Anti-NEIL2 (Endonuclease 8-like 2, DNA Glycosylase/AP Lyase Neil2, DNA-(apurinic Or Apyrimidinic Site) Lyase Neil2, Endonuclease VIII-like 2, Nei Homolog 2, Nei-like Protein 2, FLJ31644, MGC2832, MGC4505, NEH2, NEI2) (FITC)
130268-FITC Mouse Anti-NEIL2 (Endonuclease 8-like 2, DNA Glycosylase/AP Lyase Neil2, DNA-(apurinic Or Apyrimidinic Site) Lyase Neil2, Endonuclease VIII-like 2, Nei Homolog 2, Nei-like Protein 2, FLJ31644, MGC2832, MGC4505, NEH2, NEI2) (FITC)
商品编号：
130268-FITC
品牌：
USbiological
市场价：
¥13620.00
美元价：
5788.50
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
InvolvedinbaseexcisionrepairofDNAdamagedbyoxidationorbymutagenicagents.HasDNAglycosylaseactivitytowards5-hydroxyuracilandotheroxidizedderivativesofcytosinewithapreferenceformismatcheddoublestrandedDNA(DNAbubbles).HaslowornoDNAglycosylaseactivitytowardsthymineglycol,2-hydroxyadenine,hypoxanthineand8-oxoguanine.HasAP(apurinic/apyrimidinic)lyaseactivityandintroducesnicksintheDNAstrand.CleavestheDNAbackbonebybeta-deltaeliminationtogenerateasingle-strandbreakatthesiteoftheremovedbasewithboth3'-and5'-phosphates.
Applications
SuitableforuseinELISAandWesternBlot.Otherapplicationsnottested.
RecommendedDilutions
SandwichELISA:ThedetectionlimitforrecombinantGSTtaggedNEIL2is~1ng/mlasacaptureantibody.Optimaldilutionstobedeterminedbytheresearcher.
AminoAcidSequence
MPEGPLVRKFHHLVSPFVGQQVVKTGGSSKKLQPASLQSLWLQDTQVHGKKLFLRFDLDEEMGPPGSSPTPEPPQKEVQKEGAADPKQVGEPSGQKTLDGSSRSAELVPQGEDDSEYLERDAPAGDAGRWLRVSFGLFGSVWVNDFSRAKKANKRGDWRDPSPRLVLHFGGGGFLAFYNCQLSWSSSPVVTPTCDILSEKFHRGQALEALGQAQPVCYTLLDQRYFSGLGNIIKNEALYRAGIHPLSLGSVLSASRREVLVDHVVEFSTAWLQGKFQGRPQHTQVYQKEQCPAGHQVMKEAFGPEDGLQRLTWWCPQCQPQLSEEPEQCQFS
StorageandStABIlity
Storeproductat4°Ciftobeusedimmediatelywithintwoweeks.Forlong-termstorage,aliquottoavoidrepeatedfreezingandthawingandstoreat-20°C.Aliquotsarestableat-20°Cfor12monthsafterreceipt.Diluterequiredamountonlypriortoimmediateuse.Furtherdilutionscanbemadeinassaybuffer.Caution:FITCconjugatesaresensitivetolight.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.
Note:Applicationsarebasedonunconjugatedantibody.
品牌介绍
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