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当前位置: 首页 > 产品中心 > Sandwich_method_ELISA > Usbio/384863 Natalizumab (Tysabri®) BioAssay™ ELISA Kit/384863/96Tests
商品详细Usbio/384863 Natalizumab (Tysabri®) BioAssay™ ELISA Kit/384863/96Tests
Usbio/384863  Natalizumab (Tysabri®) BioAssay™ ELISA Kit/384863/96Tests
Usbio/384863 Natalizumab (Tysabri®) BioAssay™ ELISA Kit/384863/96Tests
商品编号: 384863
品牌: USbiological
市场价: ¥22280.00
美元价: 9469.00
产地: 美国(厂家直采)
公司:
产品分类: 夹心法ELISA
公司分类: Sandwich_method_ELISA
联系Q Q: 3392242852
电话号码: 4000-520-616
电子邮箱: info@ebiomall.com
商品介绍

Natalizumab(Tysabri®)isahumanizedmonoclonalantibodyagainstthecelladhesionmoleculealpha4-integrinusedinthetreatmentofmultiplesclerosisandCrohn'sdisease.Tysabri®andwaspreviouslynamed|Antegren®.NatalizumabisadmiNISTeredbyintravenousinfusionevery28daysandreducestheABIlityofinflammatoryimmunecellstoattachtoandpassthroughthecelllayersliningtheintestinesandblood–brainbarrier

SampleType
Serumandplasma
IntendedUse
TheNatalizumabBioAssay™ELISAkitisdesignedtomeasurefreeNatalizumabwithhighspecificityandsensitivityinBIOLOGicalmatrices.
Sensitivity
1.5ng/ml
Recovery
250ng/mLofNatalizumabwasspikedin10lotsofhumanserum.Recoveryrangesarefrom90-108%withanaveragerecoveryof96%.
Precision:t|Intra-assayCV:<10%|Inter-assayCV:<10%.
Specificity
HumanIgG1andrituximabpreparedat250ng/mLwereassayedandexhibitednocrossreactivityorinterference.
TestPrinciple
Thisassayemploysthesandwichenzymeimmunoassaytechnique.Captureantibodyiscoatedontoa96wellmicroplate.CalibratorandtestsamplesarePipettedintotheappropriatewells.Natalizumabpresentinbiologicalmatricesisboundbytheimmobilizedanti-Natalizumabantibody.Afterwashingawayanyunboundsubstances,enzymelinkedanti-Natalizumabantibodyisaddedtothewells.Theplateiswashedtoremoveanyunboundantibody-enzymereagentandasubstratesolutionisaddedtothewellsforcolordevelopment.ThecolordevelopmentisproportionaltotheamountofNatalizumabpresentintestsamples.Thecolordevelopmentisstoppedandtheintensityofthecolorismeasured.
KitComponents
Coatedmicrotiterplate,1x96wellsCalibratordiluent,1x1.8mlCalibrator(0.5mg/mL),1x12ulWashbuffer,10X,1x25mlAssaybuffer1x50mlDetectionreagent,1000X,1x17ulTMB,1x12mlTMBstopsolution,1x12ml
StorageandStability
Storekitcomponentsat-20°Cunlessspecifiedotherwise.Unopenedkitisstablefor6monthsafterreceipt.Formaximumrecoveryofproduct,centrifugesmalltubesonpulsesettingpriortoopening.
品牌介绍
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