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M1210-04C-AP Rat Anti-Macrophage Scavenger Receptor Type I (MSR1, CD204, Macrophage Acetylated LDL Receptor I And II, Macrophage Scavenger Receptor Types I And II, PhSR1, Scavenger Receptor Class A Member 1, SCARA1, Scavenger Receptor Type A, SRA, Scvr) (
M1210-04C-AP Rat Anti-Macrophage Scavenger Receptor Type I (MSR1, CD204, Macrophage Acetylated LDL Receptor I And II, Macrophage Scavenger Receptor Types I And II, PhSR1, Scavenger Receptor Class A Member 1, SCARA1, Scavenger Receptor Type A, SRA, Scvr) (
商品编号：
M1210-04C-AP
品牌：
USbiological
市场价：
¥13320.00
美元价：
5661.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
ThemurinescavengerreceptorclassA(SRA),typeIandIIisalsoknownasCD204.CD204isexpressedbytissuemacrophagesandfunctionsbothasanendocyticreceptorforlipoproteinsandasanadhesionreceptorformacrophagesbindingtoligandrichtissuese.g.atheroscleroticlesions.Inhibitstheuptakeofacetylatedlow-densitylipoproteinsandalsoinhibitsdivalentcationindependentadhesion.
Applications
SuitableforuseinELISA,WesternBlot,ImmunohistochemistryandImmunoprecipitation.Otherapplicationsnottested.RecommendedDilutions
Hybridoma:|Y3ratmyelomacellswithspleencellsfromAOrats.
StorageandStABIlity
Storeproductat4°C.DONOTFREEZE!Stableat4°Cfor12monthsafterreceiptasanundilutedliquid.Diluterequiredamountonlypriortoimmediateuse.Furtherdilutionscanbemadeinassaybuffer.Formaximumrecoveryofproduct,centrifugetheoriginalvialpriortoremovingthecap.
Note:Applicationsarebasedonunconjugatedantibody.
References
1.Fraser,I.P.etal.(1993)Divalentcation-independentmacrophageadhesioninhibitedbymonoclonalantibodytomurinescavengerreceptor.Nature364:343-346.2.deVilliers,W.J.S.etal.(1994)Macrophage-colony-stimulatingfactorselectivelyenhancesmacrophagescavengerreceptorexpressionandfunctionJ.Exp.Med.180:705-709.3.Hughes,D.A.etal.(1995)MurineMacrophageScavengerReceptor:invivoexpressionandfunctionasreceptorformacrophageadhesioninlymphoidandnon-lymphoidorgans.Eur.J.Immunol.25:466-473.4.Bell,M.D.etal.(1994)UpregulationofthemacrophagescavengerreceptorinresponsetodifferentformsofinjuryintheCNS.J.Neurocytol.23:605-613.5.Hughes,D.A.etal.(1994)MurineMacrophageScavengerReceptor:AdhesionfunctionandExpression.Imm.Letts.43:7-14.6.Rosen,H.andHughes,D.A.(1995)AssaysofMyeloidCellFunction:Migrationandadhesioninvivo.WeirHandbookofExperimentalImmunology.London,BlackwellScientificPublications.5th,ed.InPress.7.Daugherty,A.etal.(2000)PolymorphismofclassAscavengerreceptorsinC57BL/6mice.J.LipidRes41:1568-1577.8.Moldenhauer,L.M.etal.(2010)GM-CSFIsanEssentialRegulatorofTCellActivationCompetenceinUterineDendriticCellsduringEarlyPregnancyinMice.JImmunol.185:7085-7096.9.Luechtenborg,B.etal.(2008)FunctionofscavengerreceptorclassAtypeI/IIisnotimportantforsmoothmusclefoamcellformation.EurJCellBiol.87:91-9.10.Sever-Chroneos,Z.etal.(2011)SurfactantProteinA(SP-A)-mediatedClearanceofStaphylococcusaureusInvolvesBindingofSP-AtotheStaphylococcalAdhesinEapandtheMacrophageReceptorsSP-AReceptor210andScavengerReceptorClassA.JBiolChem.286:4854-70.11.Yang,C.N.etal.(2011)MechanismmediatingoligomericAßclearancebynaïveprimarymicroglia.NeurobiolDis.Jan8.12.Hald,A.etal.(2011)MMP9isprotectiveagainstlethalinflammatorymasslesionsinthemousecolon.DisModelMech.4:212-27.13.Swain,S.D.etal.(2011)Pneumocystisinfectioninanimmunocompetenthostcanpromotecollateralsensitizationtorespiratoryantigens.InfectImmun.Feb22.14.Nikolic,D.etal.(2011)SR-AligandandM-CSFdynamicallyregulateSR-Aexpressionandfunctioninprimarymacrophagesviap38MAPKactivation.BMCImmunol.12:37.15.Zaynagetdinov,R.etal.(2011)ACriticalRoleforMacrophagesinPromotionofUrethane-InducedLungCarcinogenesis.JImmunol.Nov2.16.Kaur,H.etal.(2003)Identificationofascavengerreceptorhomologueonnonspecificcytotoxiccellsandevidenceforbindingtooligodeoxyguanosine.FishShellfishImmunol.15:169-81.17.Kaur,H.etal.(2004)Single-baseoligodeoxyguanosine-bindingproteinsonnonspecificcytotoxiccells:identificationofanewclassofpattern-recognitionreceptors.ScandJImmunol.60:238-48.品牌介绍
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