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Usbio/298112 Mouse Anti-4-Hydroxy-2-Nonenal (4-HNE, Hydroxynonenal, 4 HNE)/298112/20ug
Usbio/298112 Mouse Anti-4-Hydroxy-2-Nonenal (4-HNE, Hydroxynonenal, 4 HNE)/298112/20ug
商品编号：
298112
品牌：
USbiological
市场价：
¥11520.00
美元价：
4896.00
产品分类：
功能性抗体
公司分类：
Functional_antibody
联系Q Q：
3392242852
电话号码：
4000-520-616
电子邮箱：
info@ebiomall.com
商品介绍
Aldehydicproductsoflipidperoxidation,suchas4hydroxynonenal(4HNE),havebeenimplicatedintheetiologyofpathologicalchangesunderoxidativestressasakeymediatorofoxidativestressinducedcelldeath.Itisastableproductoflipidperoxidation,isproarrhythmicandmaycontributetothecytotoxiceffectsofoxidativestress.
Applications:|SuitableforuseinELISA,WesternBlotandImmunohistochemistry.Otherapplicationsnottested.
RecommendedDilution
WesternBlot:15ug/mlImmunohistochemistry(Paraffin):10ug/ml;cryosectionsOptimaldilutionstobedeterminedbytheresearcher.
StorageandStABIlity
Lyophilizedpowdermaybestoredat-20°C.Stablefor12monthsafterreceiptat-20°C.ReconstitutewithsterileddH2O.Aliquottoavoidrepeatedfreezingandthawing.Storeat-20°C.Reconstitutedproductisstablefor12monthsat-20°C.Formaximumrecoveryofproduct,centrifugetheoriginalvialafterthawingandpriortoremovingthecap.Furtherdilutionscanbemadeinassaybuffer.
References
1.ToyokuniS,MiyakeN,HiaiH,HagiwaraM,KawakishiS,OsawaT,UchidaK(1995).Themonclonal|antibodyspecificforthe4-hydroxy-2-nonenalhistidineadduct.FEBSLett.359,p189-191.2.TanakaT,NishiyamaY,OkadaK,HirotaK,MatsuiM,YodoiJ,HiaiH,ToyokuniS(1997).Inductionandnucleartranslocationofthioredoxinbyoxidativedamageinthemousekidney:independenceoftubularnecrosisandsulfhydryldepletion.Lab.Invest.77(2),p145-155.3.KondoS,ToyokuniS,IwasaY,TanakaT,OnoderaH,HiaiH,ImamuraM(1999).Persistentoxidativestressinhumancolorectalcarcinoma,butnotinadenoma.FreeRADIcBiolMed27(3-4):401-410.4.YamadaS,FunadaT,ShibataN,KobayashiM,KawaiY,TatsudaE,FuruhataA,UchidaK(2004).Protein-bound4-hydroxy-2-hexenalasaMarkerofoxidizedn-3polyunsaturatedfattyacids.JLipidRes45(4):626-634.品牌介绍
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